The main street of the city, which runs in North-south direction, is 1 km long and divides the city into two. It is flanked by porticos and monumental public buildings. Frontinus street is closed at each end by honorary gates

The Main Street and the gates

Frontinus Gate: This is the monumental entrance to the Roman city and leads onto the large plateia, 14m wide, wich crosses the whole settlement, exiting a gate at the opposite side, to connect with the road that goes to Laodicea on the Lykos and then Colossae. It is worth admiring the well preserved structure with three openings, in carefully squared travertine blocks, with elegant arches decorated with elegant arches decorated with a simple cornice moulding, flanked by two round towers that recall Hellenistic city Gates such as that of the Pamphilian city of Perge, near Antalya.

The North Byzantine Gate: The North gate forms part of a fortification system built at Hierapolis in Theodosian times (end of the fourth century AD) and is its monumental entrance, matched by a symmetrical gate to the South of the city. Built of reused material from the demolition of the Agora, it is flanked by two square towers, as in other nearby cities such as Blaundus. Four large marble brackets with heads of lions, of panther ond of a Gorgon were found collapsed in front of the gate. They are quti expressive and, whilst belonging to antique buildings, were evidently reused as apotropaic elements on the two sides of the gate so as to ward off evil enfluence.